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1-Nitropyrene oxidative metabolism

Bond (135) found that S9 preparations from rat nasal tissue have twice the specific activity for the oxidative metabolism of 1-nitropyrene as liver S9 and 10 times the activity of lung S9. Each S9 preparation gave similar metabolic profiles with the... [Pg.386]

Nitro polycyclic aromatic hydrocarbons are environmental contaminants which have been detected in airborne particulates, coal fly ash, diesel emission and carbon black photocopier toners. These compounds are metabolized Tn vitro to genotoxic agents through ring oxidation and/or nitroreduction. The details of these metabolic pathways are considered using 4-nitrobiphenyl, 1- and 2-nitronaphthalene, 5-nitro-acenaphthene, 7-nitrobenz[a]anthracene, 6-nitro-chrysene, 1-nitropyrene, 1,3-, 1,6- and 1,8-dinitro-pyrene, and 1-, 3- and 6-nitrobenzo[a] pyrene as examples ... [Pg.374]

See other pages where 1-Nitropyrene oxidative metabolism is mentioned: [Pg.386]    [Pg.389]    [Pg.374]    [Pg.392]    [Pg.393]    [Pg.220]    [Pg.103]    [Pg.104]    [Pg.104]   
See also in sourсe #XX -- [ Pg.383 ]



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