Nitroglycerine molecular weight

An interesting property of nitric esters, namely their ability to catalyse certain reactions of addition polymerization has been reported recently. Initially this observation was made by Rogovin and Tsaplina [66] while polymerizing styrene and methyl methacrylate in the presence of nitroglycerine. The latter amounted to 5-20 parts by weight corresponding to about 10% of the polymerized substance. As a result of the increased polymerization speed, the molecular weight of the polymer is smaller than if polymerization is carried out slowly. 

As a result of salivary flow, drag concentrations in this region are sustained only for a relatively short period of time, probably in the order of minutes. For these reasons, the sublingual route is ideally suited to the delivery of low molecular weight lipophilic drags where rapid onset of action is required (e.g. nitroglycerin). Dosage forms that have been developed that are suitable for these types of applications include ... 

Low-molecular-weight heparins Measles, mumps, and rubella vaccine Meclofenamate Mesalamine MethyIdopa Minoxidil Morphine Nalidixic acid Naphazoline Naproxen Nitroglycerin Octreotide Oxacillin... 

Nitration of low molecular weight polyols, rather than polysaccharides, was initiated by Sobrero, who produced glyceryl trinitrate (nitroglycerin) in 1846 and mannitol hexanitrate in 1847, although the explosive properties of hexani-tromannitol were not examined until 1878, by Sokolov.During the various arms races between the Crimean War and the end of World War II, a host of polyol nitrates were investigated some of the compounds that have remained... 

A remarkable special property of nitrate esters is the ability to catalyze some additional polymerization reactions [42]. In nitroglycerine, both styrene and methyl methacrylate can be self-polymerized. If the amount of nitroglycerine is up to 5-20 portion (weight fraction), equals to 10 % of polymers, the polymerization rate will be fastened. The molecular weight of polymers is less than that obtained through slowly polymerization or in situ anionic polymerization. 

---