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Nitrogen mustards lethality

To understand better the mechanism by which alkylating agents in general and nitrogen mustards in particular bring about lethal cellular damage, it is useful to review briefly the... [Pg.105]

Sulfur mustards have become one of the most lethal weapons in chemical warfare. These substances were developed between World Wars 1 and II, along with some other lethal agents, such as nerve gases, nitrogen mustards, and phosgene. Sulfur mustards rank among the worst toxic military poisons, second to the nerve agents in terms of potential for mass casualties. These substances are also further discussed in Part A, Section XII of this book. [Pg.669]

Among the most biologically reactive alkylating agents are the nitrogen and sulfur "mustards" such as bis-(2-chloroethyl)sulfide. These toxic bifunctional compounds cause lethal crosslinking of DNA chains... [Pg.1584]

See other pages where Nitrogen mustards lethality is mentioned: [Pg.106]    [Pg.446]    [Pg.40]    [Pg.68]    [Pg.101]    [Pg.101]    [Pg.103]    [Pg.3003]    [Pg.146]    [Pg.133]    [Pg.7]    [Pg.3]    [Pg.43]    [Pg.77]    [Pg.78]    [Pg.81]    [Pg.81]    [Pg.491]    [Pg.107]   
See also in sourсe #XX -- [ Pg.101 ]

See also in sourсe #XX -- [ Pg.78 ]



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