4- Nitro-3-tolunitrile

Nitro-p-tolunitrile Stannous chloride Sulfuric acid Ammonia... 

Preparation of 2-Nitro-4,4 -Dicyanostilbene 10 grams of 2-nitro-p-tolunitrile and 8.1 grams... 

In the next step a mixture of 0.43 mole of S-nitro-o-tolunitrile, 0.56 mole of nitronium telrafluoroborate. and 350 g. of tetramethylene sulfone is stirred under reflux and heated until a thermometer in the liquid registers 100-115°. This temperature is maintained for I hr., and the mixture is then let C(h>I and poured into ice waler. C rystullizution of the crude product ffom HO ml. of methanol gives pure 3,5-dinilro-[Pg.374]

Preparation of 2-Nitro-4,4 -Dicyanostilbene 10 grams of 2-nitro-p-tolunitrile and 8.1 grams of 4-cyano-benzaldehyde were heated to 170° to 180°C, 1.2 and 0.6 cc of piperidine were added at quarter-hour intervals, heating was continued ifor a further one and a quarter hours, the product cooled, triturated with glacial acetic acid and filtered. The residue was crystallized from glacial acetic acid as yellow needles, MP 290°C. 

Other Names Acetonitrile, (p-nitrophenyl)- (p-Nitrophenyl)acetonitrile 4-Nitrobenzeneacetoni-trile 4-Nitrobenzyl cyanide 4-Nitrophenylacetonitrile NSC 5396 p-Nitro-a-tolunitrile p-Nitro-benzeneacetonitrile p-Nitrobenzyl cyanide CA Index Name Benzeneacetonitrile, 4-nitro-CAS Registry Number 555-21-5 Merck Index Number 6591 Chemical Structure... 

Aq. KOH added dropise to an ice-cooled soln. of a,a,a-trifluoro-2,6-dinitro-p-tolunitrile and methyl thioglycolate in dimethylformamide, and stirred 5 min. in the cold methyl 3-amino-4-nitro-6-trifiuoromethylbenzo[b]thiophene-2-carboxylate. Y 80%. - Nucleophilic displacement of ar. nitro groups is almost as easy as that of ar. fluorine groups and easier than that of ar. chlorine groups. F. e. s. J. R. Beck, J. Org. Chem. 57, 3224 (1972). 

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