2-Nitro-4-methoxy benzaldehyde

Decarbonylation of 2-[ F]fluorobenzaldehydes has been used to synthesize labeled arenes with nonactivated substituents, e.g., 4-bromo-[ F]fiuorobenzene from 3-bromo-6-nitrobenzaldehyde (Chakraborty and Kilbourn 1991a). This methodology was also applied to [ Fjfluoroarylketones (Allain-Barbier et al. 1998 Forngren et al. 1998) and to mono- to tetra-methoxy-substituted [ F]fluorobenzenes from the corresponding 2-nitro(methoxy) benzaldehydes (Shen et al. 2009). In the latter study they identified side products, which derived from demethylation of methoxy groups and intramolecular redox processes that reduced the radiochemical yields. 

Miscellaneous Identified Inhibitors. 3-Acetyl-6-methoxy-benzaldehyde is present in the leaves of the desert shrub Encelia farinosa. It is apparently leached from the leaves and washed into the soil by rain. Concentrations of approximately 0.5 mg. per gram of dried leaf material have been measured. In sand culture studies, growth of tomato seedlings was inhibited by 50 p.p.m. while 115 p.p.m. reduced growth by 50% (53). A concentration of 250 p.p.m. killed the test plants within one day. The structure was confirmed by synthesis, and the synthetic material was shown to be as active as the natural product (54). Derivatives were also prepared in which a cyano, nitro, or amino group was substituted for the aldehyde moiety. The amino derivative was reported to be the most highly toxic. 

Nitro-benzaldehyd (4-Methoxy-benzyl)-(4-nitro-benzyl)-amin — 35% 4-Methoxy-benzaldehyd... 

Chlor-3- methoxy-benzaldehyd- [4-nitro-phenylhydrazon] 15 II197. 

Nitro compounds have also been reported to undergo photocyclizations. The intermediacy of an isoxazoline in the photorearrangement of o-nitro-benzaldehyde to o-nitrosobenzoic acid is now in doubt,318 but intramolecular hydrogen abstraction by an excited nitro group in nitrobenzene derivatives can result in the formation of heterocycles. 4-tm-Butyl-3-methoxy-2,6-dinitrotoluene (384) on irradiation in methanolic sodium hydroxide solution... 

Benzene, 2-ethyl-5-isooctyl-4-methoxy-l, 3-dinitro Benzene, l-isoheptyl-2-methoxy-4-methyl-3, 5-dinitro Benzene, l-isooctyl-2-methoxy-4-methyl-3, 5-dinitro Ethanone, 1- [3-(l,l-dimethylethyl)-2-methoxy-5-nitrophenyl Benzene, 1,3-dibromo-2-isopropyl-5-methoxy-4-nitro Benzene, 1,3-BIS- (1, l-dimethylethyl)-5-nitro Benzaldehyde, 5 (l,l-dimethylethyl)-2-methoxy-3-nitro Benzene, 1, 5-BIS- (1, l-dimethylethyl)-2 methoxy-4 methyl... 

Abietic ACID, 32, 1 acid sodium salt of, 32, 4 diamylamine salt of, 32, 2 Acetaldehyde, 36, 60 Acetaldehyde, diphenyl-, 38, 26 Acetal formation, from pentaerythritol and benzaldehyde, 38, 65 Acetamide, 31, 17 Acetamide, N-bromo, 31,17 a-PHENYL-, 32, 92 Acetanilide, < -benzoyl-, 37, 2 Acetanilide, -benzoyl-2-methoxy-4-nitro, 37, 4... 

Benzaldehyd 4-Methoxy-3-nitro- -chlorimin E14b, 283 (R —CHO + NH2C1)... 

The second-order rate constants for the reaction of OH radical with meta- and para-isomers of hydroxy-, methoxy-, chloro- and nitro-benzaldehydes are in the range (2.8 to 12) x 10 dm mol s . The higher rate in methoxybenzaldehyde is attributed to the activation of the ring by the electron-donating -OCH3 group. 

The reaction has been carried out on large- and small-scale batches (Note 10). This modification, as exemplified by 3,4,5-trimethoxybenzaldehyde, has been applied by the submitters to the preparation of other aldehydes such as 3,4-dimethyl-benzaldehyde (90% yield), 3-benzyloxy-4,5-dimethoxybenz-aldehyde (88% yield, with retention of the benzyl group), and 3-methoxy-4-nitrobenzaldehyde (62% yield, with retention of the nitro group). 

Auf diese Weise wird die Decarbonylierung des Trimethoxybenzaldehydes vermieden, die beim Arbeiten unter klassischen Reaktionsbedingungen" auftreten kann22. Auf die glei-che Weise werden 3-Methoxy-4-nitro- (62%), 3,4-Dimethyl- (90%) und 3-Benzyloxy-4,5-dimethoxy-benzaldehyd (88%) erhalten. 

M ethoxy-benzaldehyd 2-Methoxy-benzoesaure 4-Nitro-1 -m ethoxy-benzol... 

In general, the Perkin reaction is limited to aromatic aldehydes. The activity of substituted benzaldehydes in the Perkin reaction is similar to the trends observed in other reactions involving the carbonyl group. A halogen (28) or nitro (34) group in any position increases the rate of reaction and the yield a methyl group (26) in any position decreases the rate and yield, and this effect falls off in the order ortho > meta > para A methoxy group in the ortho position (30) has a small favorable influence, but in the para position (32) it has a definite unfavorable effect on the rate and yield. 

Benzaldehyde, nt-HYDROXY-, 26, 55 Benzaldehyde, > -methoxy-, 29, 63 Benzaldehyde, o-nitro-, 24, 75 Benzaldehyde, tiMiasiO-, dihetbyi acetal, 29, 72... 

The kinetics of oxidation of substituted mandelic acids (a-hydroxyphenylacetic acid) in sulfate and mixed perchlorate/sulfate solutions are the subject of the four reports from Calvaruso et al. (1981a, b) and Arcoleo et al. (1977,1979). The oxidation reaction yields (substituted) benzaldehydes upon decarboxylation of mandelic acid. The oxidation of the p-nitro and p-methoxy derivatives in sulfuric acid proceeds without significant complex formation. The authors conclude that the reaction proceeds through two reactive Ce(IV) species,... 

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