Nisin-controlled gene expression system

Mierau, I. and Kleerebezem, M. (2005) 10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis. Applied Microbiology and Biotechnology, 68 (6), 705—717. 

Mierau, I., Leij, R, van Swam, I.,et al. (2005) Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE the case of lysostaphin. Microb Cell Fact 4, 15. 

De Ruyter, P. G. G.A., Kuipers, O. R, De Vos, W. M. (1996). Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin. Applied and Environmental Microbiology, 62, 3662-3667. 

Nisin-controlled gene expression (NICE) The NICE system is the most commonly used inducible expression system for heterologous proteins production in LAB. The synthesis. 

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