Nicotinic acid aureus

Similar experiments by Lwoff showed nicotinic acid was an essential growth factor for Hemophilus bacteria and also for Staph, aureus. By the 1940s an aphorism had been coined Growth factors for microorganisms are B vitamins for higher animals. ... [Pg.37]

Nicotinic acid and the growth of Staphylococcus aureus. Nature (Lon-... [Pg.213]

Derivatives of nicotinic acid which were ineffective for Staph, aureus, Proteus vulgaris and pea roots —pyridine-3,4-dicarboxylic acid (cinchomeronic acid) pyridine-3,5-dicarbo.xylic acid (dinicotinic acid) 3-amino-pyridine trigonelline are-coline. 6-Methyl-nicotinic acid was inactive for dysentery bacilli. Derivatives differing in structure more widely were inactive. [Pg.183]

There are some quantitative differences in the ability of different bacteria to use a given compound and in the ease with which different compounds can be used by the same species. Thus, among alkyl esters of nicotinic acid, the methyl ester gave delayed growth with Staph, aureus, the time-lag being interpreted as due to the need to hydrolyze to the free acid prepara-toiy to amide and phosphopyridine nucleotide synthesis (159). With dysentery bacilli [3 strains of Shigella paradysenteriae (186)] the methyl... [Pg.184]

Staph, aureus Amino acids -t- nicotinic acid 2, 3,4 159... [Pg.190]

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