Nicotine patch adverse effects

The effect of transdermal nicotine on concomitant medications has been reported in an open non-comparative study of 80 smokers (42 men and 38 women) who used 24-hour nicotine patches (10). Adverse effects included itching and local erythema, insomnia, and abnormal taste sensations. Two subjects withdrew because of adverse effects. At 12 weeks, 17 were non-smokers. At 26 weeks, 19 were non-smokers and a further 14 had reduced their use of cigarettes significantly. 

Local skin reactions to transdermal nicotine patches have been reported (31). Other local adverse effects, including erythema with edema, erosions, and systemic skin reactions have also been described (32). 

No. The nicotine patch in particular is safe and has been shown not to cause adverse cardiovascular effects. 

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