Nicotine Nitrous oxide

Inhalation (IH) The administration of volatile gases and vapours, followed by drug absorption in the lungs or nasal mucosa. Examples include general anaesthetics like nitrous oxide, nicotine from the tar droplets in tobacco smoke, cannabinoids from cannabis leaf smoke and various opiates from burning opium resin. 

Drugs may be solid at room temperature (eg, aspirin, atropine), liquid (eg, nicotine, ethanol), or gaseous (eg, nitrous oxide). These factors often determine the best route of administration. The most common routes of administration are described in Chapter 3. The various classes of organic compounds—carbohydrates, proteins, lipids, and their constituents—are all represented in pharmacology. 

And somewhat ironically, nitrous oxide appears to have some use as an treatment for withdrawal symptoms. Several South African studies have demonstrated the usefulness of nitrous oxide in treating withdrawal symptoms and reducing cravings during alcohol, marijuana, and nicotine detoxification. And in early 2002, a small study published in Clinical Psychiatry found that the gas may also be helpful in helping smokers kick the habit. Researchers found that 92% of patients who inhaled a 50%/50% mixture of nitrous oxide and oxygen... 

A 22-year-old woman in good health was anaesthetised for surgery with nitrous oxide/oxygen and isoflurane. Twenty minutes after induction she was given an injeetion of 0.2 units of vasopressin into the eervix. Within seeonds she developed severe hypotension and bradycardia, and over the next 30 minutes blood pressures as low as 70/35 mmHg and heart rates as low as 38 bpm were recorded. She was treated with atropine and adrenaline (epinephrine), and eventually made a full recovery. This patient was wearing a transdermal nicotine patch. ... 

NICKEL CHLORIDE NICKEL NITRATE NICKEL sulphate NICOTINE NICOTINE ACID NITROUS OXIDE OILS FATS OIL, SOUR CRUDE OLEIC ACID OXALIC ACID OXYGEN OZONE... 

Recently, a phenomenon labeled thirdhand smoke has been attributed to the reaction of nicotine with ambient nitrous oxide on environmental surfaces to produce the carcinogenic nitrosamines. Surfaces shown to promote nitrosamine include ubiquitous cellulosic material [55],... 

Nitrosyl chloride in iV,iV-dimethylfonnamide at low temperature has been used for the convenient deamination of adenosine, adenosine 5 -phosphate, adenosine 5 -triphosphate, and their iV -oxides to the corresponding inosine derivatives. Nitrous anhydride (N2O3) has been used to convert the coenzyme adenine-nicotinamide dinucleotide into hypo-xanthine-nicotinic acid dinucleotide. 

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