Nicotinamide adenine dinucleotide fatty acid biosynthesis

The direct oxidation of glucose via pentoses is of significance for the formation of pentoses (and indirectly for nucleic acid synthesis). Nicotinamide-adenine dinucleotide phosphate (NADP) is the hydrogen acceptor here. The reduced form , NADPH2, is necessary for many synthetic processes, e.g., for the synthesis of fatty acids, for the biosynthesis of cholesterol, and for hydroxylation reactions. The direct oxidation of glucose to pentoses, therefore, has this second function It provides the necessary reduction equivalents for other anabolic processes. It is not a source of energy. 

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