Nickel chloride methoxide

Methanol, Hydrogen, Raney nickel catalyst, 0484 Methoxyacetyl chloride, 1165 4-Methoxy-3-nitrobenzoyl chloride, 2916 Methyl formate, Methanol, Sodium methoxide, 0834 3-Methyl-2-penten-4-yn-l-ol, 2384 Nitric acid, 4436... 

Lithium aluminum hydride, 61, 62, 282 Lithium aluminum hydride-Bis-(cyclopentadienyl)nickel, 158 Lithium aluminum hydride-Cerium(III) chloride, 159 Lithium aluminum hydride-Hexa-methylphosphoric triamide, 159 Lithium aluminum hydride-Potassium methoxide, 159... 

Fithium tetrahydroaluminate, Fluoroamides, 0075 Lithium tetrahydroaluminate, Water, 0075 Lithium, 1,2-Diaminoethane, Tetralin, 4675 Magnesium, Barium carbonate, Water, 4685 Maleic anhydride, Bases, or Cations, 1400 Mercaptoacetonitrile, 0763 t Methanol, Hydrogen, Raney nickel catalyst, 0482 4-Methoxy-3-nitrobenzoyl chloride, 2911 Methoxyacetyl chloride, 1161 t Methyl formate, Methanol, Sodium methoxide, 0830 3-Methyl-2-penten-4-yn-l-ol, 2378 Nitric acid, 4430... 

A plausible mechanism for the reaction includes several organometallic species that are sensitive to reactive moieties elsewhere in the molecule. If a chloro, chloromethyl, or mesyloxymethyl substituent is attached vicinal to the 1,1 -dibromo moiety, efficient ring opening occurs prior to carbonylation and P,y- and y, -unsaturated acid derivatives are formed. Reductive carbonylation has also been achieved with 1,1-dibromocyclopropanes using an excess of pentacarbonyliron in dimethylformamide with added methanol or sodium methoxide, or cobalt(II) chloride and nickel(ll) cyanide under phase-transfer conditions in a carbon monoxide atmosphere. However, the yield of cyclopropanecarboxylic acid derivatives is low, and when pentacarbonyliron is used the amount of monobromides is fairly high. ... 

Cyclizatton Boron trifluoride etherate. Ion-exchange resin. Lithium, diethylamide. Mercuric acetate(then sodium borohydride). Methanesulfonic acid. Nickel carbonyl. Polyphosphate ester. Sodium aluminum chloride. Sodium methoxide. Trifluoracetic acid. 

The nitroketone 118 (see Section IV,B,1) was treated with hydrogen chloride in ethanedithiol to afford the thioketal 119. Reduction of 119 with zinc and acetic acid and further treatment with Raney nickel in ethanol furnished lactam 120. Hydrolysis of 120 in aqueous methanol containing K2C03 gave 121, which on LAH reduction horded the amine 122. On treatment with sodium methoxide, the iV-chloro derivative of 122 gave verazine (123) (215). 

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