Nomenclature niacin

The answer is e. (Murray, pp 627-661. Sciiver, pp 3897-3964. Sack, pp 121-138. Wilson, pp 287-320.) Ascorbic acid (vitamin C) is found in fresh fruits and vegetables. Deficiency of ascorbic acid produces scurvy, the sailor s disease. Ascorbic acid is necessary for the hydroxylation of proline to hydroxyproline in collagen, a process required in the formation and maintenance of connective tissue. The failure of mesenchymal cells to form collagen causes the skeletal, dental, and connective tissue deterioration seen in scurvy. Thiamine, niacin, cobalamin, and pantothenic acid can all be obtained from fish or meat products. The nomenclature of vitamins began by classifying fat-soluble vitamins as A (followed by subsequent letters of the alphabet such as D, E, and K) and water-soluble vitamins as B. Components of the B vitamin fraction were then given subscripts, e.g., thiamine (Bi), riboflavin (B2), niacin [nicotinic acid (B3)], panthothenic acid (B5), pyridoxine (Bg), and cobalamin (B ). The water-soluble vitamins C, biotin, and folic acid do not follow the B nomenclature. 

Nomenclature. Niacin (vitamin PP) group name for nicotinic acid, nicotinamide, NAD, and NADP. 

The name niacin is often used for two compounds, namely pyridine-3-carboxylic acid and pyridine-3-carboxylic acid amide. This confusion occurs because there is no consistency in the empirical nomenclature used in nutrition literature. Harris 1 lists niacin and niacinamide as the terms preferred in the United States, and nicotinic acid and nicotinic acid amide in the British literature. A convenient solution to the problem would be to use the term niacin to refer generically to the two compounds of nutritional significance as anti-pellagra factor and adopt the names nicotinic acid and nicotinamide to refer specifically to each. Nicotinamide has been adopted by the Commission for the Reform of Nomenclature in Biological Chemistry of the International Union of Pure and Applied Chemistry, and nicotinic acid is already in current use in most British, United States and other scientific literature in English. 

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