New Thinking in Research

We have read much about positive results, but do come across negative findings that we may hesitate to report. Negative findings are important to help the researcher to determine what not to do. This is a common problem for researchers who do not receive adequate funding in the initial stages of research. 

If there is no money available for fundamental research, begin working on industrial research. If you proceed logically, you will soon be doing fundamental research, and you are sure to succeed. Down syndrome has emerged as one of the most exciting and fruitful areas of research. 

The future of drug research is at stake, as stated in Molecular Medicine Today, June 1999, Disease models will not only be of educational value but will also stimulate the use and development of models that are truly relevant to human disease, which will eventually catalyze the development of safe and efficacious therapeutics for human use.  

The process by which NCEs are discovered and developed is undergoing a dramatic change. The traditional process of discovery depended only on an empirical approach to screening compounds for a novel pharmacologic activity. 

Because of the ever-increasing demand for a new drug and high-quality treatment with fewer side effects, pharmaceutical companies are facing increased pressures to develop drugs at faster rates, in greater numbers, and more cost effectively. 

---