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Neurogenesis neural cell migration

Another level of cellular adaptation to psychotropic drug exposure involves the change in neuronal number through neurogenesis. Recent research has demonstrated that in the adult hippocampus, new cells constantly arise from immature neural precursor cells in the subgranular zone of the dendate gyrus, migrate into... [Pg.41]

Fig. 2. Mechanisms of VO(OPT)-enhanced neurogenesis after brain ischemia in the hippocampal dentate gyrus. VO(OPT) inhibits protein tyrosine phosphatase IB, thereby stimulating Akt and ERK signaling. The downstream targets of Akt and ERK include HIF-la, GSK-3/3, and CREB, which are involved in the proliferation, migration, and maturation of the neural progenitor cells. Fig. 2. Mechanisms of VO(OPT)-enhanced neurogenesis after brain ischemia in the hippocampal dentate gyrus. VO(OPT) inhibits protein tyrosine phosphatase IB, thereby stimulating Akt and ERK signaling. The downstream targets of Akt and ERK include HIF-la, GSK-3/3, and CREB, which are involved in the proliferation, migration, and maturation of the neural progenitor cells.
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See also in sourсe #XX -- [ Pg.155 ]

See also in sourсe #XX -- [ Pg.155 ]



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Cell migration

Neurogenesis

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