Neurochemical parameters

Scheuhammer, A.M., Basu, N., and Burgess, N.M. et al. (2008). Relationships among mercury, selenium, and neurochemical parameters in common loons and bald eagles. Ecotoxicology 17, 93-102. 

QUESTION Have you or anyone else had the opportunity to look at the changes in the neurochemical parameters in animals that self-administer some of the amphetamines ... 

Fluctuations in the level of attention or conscious awareness are of particular interest in terms of neurochemical correlates, which may in turn help to identify mechanisms involved in maintaining normal levels of consciousness. There is little direct evidence so far concerning which particular neurochemical parameter might be implicated. However, examination of the pathophysiology of DLB suggests potential mechanisms controlling the level of consciousness. 

Glutamate Receptors and Their Association with Other Neurochemical Parameters in Excitotoxicity... 

Table 6.3 Other neurochemical parameters associated with neurotoxicity mediated by glutamate and its analogs...

Table 7.2 Excitotoxicity-mediated changes in neurochemical parameters involved in oxidative stress...

Neurochemical parameters of respective monoamines DAT-KO mice SERT-KO mice NET-KO mice... 

Although it is possible to measure certain neurochemical parameters in humans, the understanding of molecular mechanisms of lead toxicity must depend on animal experimentation. Alterations in neurochemistry may precede other neurotoxic effects and be the basis for the expressions of altered behaviour, pharmacological response or cell pathology. 

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