Neuro-pharmaceuticals

Lastly, pharmacogenomics could provide new tools for the design of more specific and active CNS pharmaceuticals. The efficacy of a broad spectrum of neuro-pharmaceutical drugs is often complicated by their inability to reach their site of action because of the BBB. One way to overcome this is to use carrier-mediated transport at the luminal and/or abluminal membranes of the endothelial cells of the BBB. This will provide a physiologically based drug delivery strategy for the brain by designing new chemical entities or fused proteins that can cross the BBB via these transporters. 

Synonyms Acecoline Choline acetate Arterocho-line 2-(Acetoxy)-N,N,N-trimethylethanaminium Ethanaminium 2-(Acetyloxy)-N,N,N-trimethyl Chemical/Pharmaceutical/Other Class Neuro-humoral transmitter Chemical Structure ... 

Kumar, R, Choonara, Y.E., Modi, G., Naidoo, D., Piflay, V., 2015. Multifunctional therapeutic delivery strategies for effective neuro-regeneration following traumatic spinal cord injury. Current Pharmaceutical Design 21, 1517-1528. 

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