Neural stem cell niche

Lim, D.A., Huang, Y.C., Alvarez-Buylla, A. (2007) The adult neural stem cell niche lessons for future neural cell replacement strategies. Neurosurg Clin N Am 18, 81-92, ix. 

Remaud S, Lopez-Juarez SA, Bolcato-BeUemin AL et al (2013) Inhibition of Sox2 expression in the adult neural stem cell niche in vivo by monocationic-based siRNA delivery. Mol Ther Nucleic Acids 2 e89... 

Hyaluronic Add is enriched in Extracellular Matrix and Neural Stem Cell Niche... 

Intriguingly, besides providing the essential function of increased tumor perfusion, new vessel growth may also promote tumor growth through a separate mechanism. Neural stem cells and likely brain tumor stem cells reside in a perivascular niche, or specialized miaoenvironment, that both supports the cells and controls proliferation and fate determination (Calabrese et al. 2007). New vessel growth may therefore, also support brain tumor stem cells by providing new niche sites. 

Taupin, P. (2006). Adult neural stem cells, neurogenic niches and cellular therapy. Stem Cell Reviews, 2, 213-9. 

The potential application of neural stem cells for spinal cord injury has been investigated by numerous studies. It has been reported that neural stem cells induced to neuronal differentiation by neurogenin-2 provided significant functional benefit following transplantation after contusion injury (Hof-stetter et al., 2005). Further, undifferentiated cells can achieve the regional appropriate phenotype specification in response to local signals in exclusive niches (Gage, 2000). 

Quinones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perex O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriquez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A (2006) Cellular composition and cy to architecture of the adult human subventricular zone A niche of neural stem cells. J Comp Neurol 494 415 34. 

Hyaluronic Acid Hydrogel A Favourable Niche for Neural Stem Cells... 

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