Neural plate regionalization

The order in which various cell fypes arise is defer-mined by fhe order in which franscripfion factors such as Hunchback, Kriippel, and ofhers are expressed. Mulfipofential neural stem cells provide fhe new cells thaf are requiredNeural tissue from a region called fhe neural plate develops info a neural fold. 

Eagleson, G. and Harris, W. (1989) Mapping the presumptive brain regions in the neural plate of Xenopus laevis. J. Neurology 21,427 440. 

The chord in T/-h embryos fails to reach the caudal region (neural tube and/or caudal part of the archenteron). As in normal mice, the chord is completely separated from the neural plate (or neural tube) and from the closely associated mesoderm. The growing end of the chord in T/- - embryos, however, was longer and bulkier than normal the base, which is linked with the neural tube, is wider than normal the ventral zone is sharper (Griineberg, 1958). 

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