Nerve in rat

Nylen P, Hagman M. 1994. Function of the auditory and visual systems, and of peripheral nerve, in rats after long-term combined exposure to -hexane and methylated benzene derivatives. II. Xylene. Pharmacol Toxicol 74(2) 124-9. 

Yonehara, N., Kudo, C., and Kamisaki, Y. (2003). Involvement of NMDA-nitric oxide pathways in the development of tactile hypersensitivity evoked by the loose-ligation of inferior alveolar nerves in rats. Brain Res. 963, 232—243. 

Springall DR, Edginton JA, Price PN, et al. 1990. Acrolein depletes the neuropeptides CGRP and substance P in sensory nerves in rat respiratory tract. Environ Health Persp 85 151-157. 

Aas, P. (1996). In vitro effects of toxogonin, HI-6 and HLd-7 on the release of [ H] acetylcholine from peripheral cholinergic nerves in rat airway smooth muscle. Eur. J. Pharmacol. 301 59-66. 

Bourre, J. M., Youyou, A., Durard, G., and Pascal, G, (1987). Slow recovery of the fatty acid composition of sciatic nerve in rats fed a diet initially low in n-3 fatty acids. Lipids 22, 535-538. 

Sufficiently high exposures to alkylbenzenes—such as //-diethylbenzene, -triethylbenzene, -trimethylbenzene, and isopropylbenzene—can produce adverse motor and sensory effects in rats after inhalation. Gagnaire et al. (1990) reported decreased motor and sensory conduction velocities and decreased amplitude of the sensory action potential of the tail nerve in rats exposed repeatedly to a mixture of diethylbenzene and its major metabolite, 1,2-diacetylbenzene (DAB). In the rat, 1,2-diethylbenzene was about 5 times more potent a neurotoxicant than -hexane (Gagnaire et al. 1990). Spinal-cord axonal swelling with partial demyelination has been associated with DAB exposure in rats (Kim et al. 2001). The neurotoxicity of 1,2-diethylbenzene appears to be related to formation of protein complexes reaction with amino acids of proteins to form pyrolated polymers that lead to protein cross links. 

Similar observations have been made with the analog of anandamide, methanandamide, which was also shown to cause eapsaiein- and capsazepine-sensitive vasorelaxation in the rat mesenteric arterial bed and isolated mesenterie arteries (Ralevic et al., 2000). However, in the same vascular bed, Harris et al. (2002) reported that vasorelaxation to anandamide was only partly sensitive to eapsaiein pretreatment. Moreover, in the presence of NO synthase bloekade, vasorelaxation due to anandamide was insensitive to eapsaiein pretreatment and thus does not occur exclusively via sensory nerves. In rat isolated coronary arteries and in the intact vasculature. White et al. (2001)... 

Matsuda LA, Lolait SJ, Brownstein MJ et al, (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA, Nature 346 561-564 McLeod RL, Parra LE, Mutter JC, Erickson CH, Carey GJ, Tulshian DB, Fawzi AB, Smith-Torhan A, Egan RW, Cuss FM et al, (2001) Nociceptin inhibits cough in the guinea-pig by activation of ORLi receptors, Br J Pharmacol 132 1175-1178 Merick B, Reid L (1971) Nerves in rat intra-acinar alveoli an electron microscope study, Respir Physiol 11 367-377... 

Figure 7.5 Optical micrographs of t-chitosan/apatite triangle tubes grafted at sciatic nerves in rats for left) 8 weeks and right) 12 weeks toluidine blue staining.

Figure 21.13 PUCL-ra -PEG nerve scaffolds prior to and after the implantation (a) the sciatic nerve was transected and bridged by a PU nerve-guided scaffold (b) PUCL-ran-PEG implanted in rat after 9 weeks was surrounded with abundant capillaries (c) PUCL-ran-PEG degraded almost completely at 20 weeks implantation (d) autologous nerve-guided defected nerve in rat after 9 weeks (e) PCL implant in rat after 9 weeks was surrounded by a layer of fibrous connective tissue (f) sibcone tube implant in rat after 9 weeks.

Glasby, MA, Gschmeissner, S, Hitchcock, RJ, and Huang, CL. 1986. Regeneration of the sciatic nerve in rats. The effect of muscle basement membrane. / Bone Jt SurgBr 68(5) 829-833. 

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