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Neonatal rat AMC

A detailed analysis of the hypoxia-sensitive, voltage-dependent K+ current in neonatal rat AMC (i.e., IKO2 in Fig. lb) indicated it consisted of a complex modulation of three different 02-sensitive K+ currents (24). Anoxia (24) or hypoxia (22 unpublished observations) inhibited both a laige-conductance, iberiotoxin-sensitive Ca +-dependent K+ current (IBKO2) and a Ca " -independent delayed... [Pg.605]

SK channels (34), and found that it depolarized neonatal rat AMC by comparable amounts to that seen with hypoxia (Fig. 3a,b). These preliminary data suggest that SK channels are open at the resting potential of neonatal rat AMC and are therefore candidates for mediating the receptor potential or membrane depolarization following elosure by hypoxia. [Pg.610]

In earher studies (22,23), hypoxic sensitivity was observed in neonatal (Pl-2) but not juvenile (PI3-20) rat AMC, consistent with a loss of the nonneurogenic... [Pg.614]

See other pages where Neonatal rat AMC is mentioned: [Pg.605]    [Pg.606]    [Pg.608]    [Pg.610]    [Pg.610]    [Pg.611]    [Pg.605]    [Pg.606]    [Pg.608]    [Pg.610]    [Pg.610]    [Pg.611]    [Pg.614]    [Pg.615]    [Pg.608]   
See also in sourсe #XX -- [ Pg.605 ]



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