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Natural product libraries using genomics

Knepper, K., GU, C., and Brase, S., Natural product-like and other biologically active heterocyclic libraries using solid-phase techniques in the post-genomic era, Comb. Chem. High Throughput Screen., 6, 673, 2003. [Pg.328]

The CFCF described by Spirin (30) is efficient for protein production using the efficient wheat germ cell-free system, as shown in the previous section. However, this system may not be suitable for massive screening of cDNA libraries for structural genomics and production of gene products. Because the CFCF apparatus is equipped with a semipermeable membrane in the reaction chamber, the system is quite complicated to manipulate. The delicate nature of the membrane can pose problems for automating the translation process. Also,... [Pg.162]

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See also in sourсe #XX -- [ Pg.29 , Pg.650 ]



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Genomic library

Natural libraries

Natural product library

Products used

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