Nasal blood flow, measurement

Clinical studies of cotton mill workers who had previously demonstrated a decreased expiratory flow measured by flow volume curves and FEV during cotton dust exposure showed an increase in WBC to 25.5% after 4 hours of exposure. Segmented neutrophils increased most (33%), while eosinophil mean counts did not change. The ratio of segmented neutrophils to epithelial cells from nasal mucosal swabs increased from 0.56 before to 1.84 after 4 hours of exposure. Peripheral blood and PMN counts increased upon exposure to cotton dust, and PMN were recruited to the nasal mucosa. Chest tightness and decreased flow were temporarily correlated with leukocyte recruitment following cotton dust exposure (2). 

Brimonidine also does not appear to alter retinal capillary blood flow or vasomotor activity of the anterior optic nerve. Measurements of blood flow velocities in central retinal, ophthalmic, nasal, and temporal posterior ciliary arteries do not change when 0.2% brimonidine is administered twice daily. When applied to human eyes, brimonidine appears to have little or no contralateral lowering effect on lOP. 

---