Naproxen piperazine

Methoxy-a-mettlyl-2-napthaleneacetate piperazine salt (2 1). EINECS 275-083-1 Naproxen piperazine salt Numidan Numide Piproxen, Anti-inflammatory analgesic antipyretic. Syntax Labs. Inc. 

Methyl esters of fatty acids (C -Cij) 2458 275-083-1 Naproxen Piperazine 2626... 

A comparable approach was used to design (piperazine-1-yl)alkyl prodrugs of naproxen (8.26), some of which improved severalfold the skin permeability of the drug [42],... 

Piproxen is a piperazine derivative of naproxen its adverse effects profile is similar to that of naproxen (4). 

The usual dose of naproxen or naproxen sodium is the equivalent of 500 mg to 1 g of naproxen daily in 2 divided doses. A dose of 10 mg per kg body-weight daily of naproxens in 2 divided doses has been used in children over 5 years of age with juvenile rheumatoid arthritis (5). In painful conditions such as dysmenorrhoea the usual initial dose is the equivalent of 500 mg of naproxen followed by 250 mg every 6 or 8 hours. In accute gout an initial dose equivalent to 750 mg of naproxen followed by 250 mg every 8 hours has been suggested (5). Rectal administration of naproxen is sometimes employed naproxen has also been used orally as the piperazine salt (5). 

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