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2.7- Naphthyridine reactions

For a detailed account of naphthyridine reactions with nitrogen nucleophiles, see chapter by van der Plas et al., p. 95 of this volume. [Pg.156]

Hermecz and co-workers used the Hantzsch 1,4-dihydropyridine synthesis in their preparation of naphthyridines. Reaction of ethyl acetoacetate 8 and hexamethylenetetramine 221 as a novel source of nitrogen... [Pg.626]

The antibacterial agent nalidixic acid [389-08-2] (37) is formed by reaction of 2-ainino-6-methylpyridine [1824-81 -3] with an alkoxymethylenemalonic ester to form the 1,8-naphthyridine carboxyUc ester followed by alkylation and ester hydrolysis (37). [Pg.328]

Naphth[2,l-d]oxazolium iodide, 2,3-dimethyl-reactions, 6, 215 Naphthyridine, amino-reactions, 2, 598 Naphthyridine, N-amino-reactions, 2, 596 Naphthyridine, 3-bromo-reactions... [Pg.707]

Quino[3,2-c][l,8]naphthyridine — see 4,5,12-Triazabenz[a]anthracenes Quinone, a-tocopheryl-synthesis, 3, 734 o-Quinone allides synthesis, 3, 741 o-Quinone diazides reactions... [Pg.835]

The 2,7-naphthyridine system 53 (Scheme 8.4.18) was combined with 2,4-dinitrochlorobenzene and 2-amino glycerol for in situ reaction of the resulting Zincke salt. The resulting naphthyridinium 54 was trapped by Bradsher cycloaddition with (Z)-vinyl ether 55, providing tetracycle 56 (X-ray) upon internal addition of one of the diastereotopic hydroxymethyl groups to the resulting iminium. This approach was also extended to the use of chiral 2,7-naphthyridinium salts, prepared via the analogous Zincke process. ... [Pg.363]

Shortly after Gabriel and Colman reported cinchomeronylacetic ester, Pels reported a similar quinolinimidoacetic ester (40) to provide a 1,6-naphthyridine (41).The structure of the isolated compound was not unambiguously determined for more than 30 years.More recently, the reaction has been shown to produce both 41 and 42 in a 3 1 ratio... [Pg.420]


See other pages where 2.7- Naphthyridine reactions is mentioned: [Pg.123]    [Pg.126]    [Pg.54]    [Pg.270]    [Pg.291]    [Pg.328]    [Pg.123]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.707]    [Pg.708]    [Pg.709]    [Pg.709]    [Pg.709]    [Pg.414]   
See also in sourсe #XX -- [ Pg.200 ]




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1,8-Naphthyridine Reissert reactions

1,8-Naphthyridine, reaction with metal

1.5- Naphthyridine ketones reactions

Alkyl-1,5-naphthyridines reactions

Amino-1,5-naphthyridines reactions

Aryl-1,5-naphthyridines reactions

By the Meissenheimer Reaction on 1,5-Naphthyridine -Oxides

Halogeno-1,5-naphthyridines reactions

Naphthyridines reactions

Nitro-1,5 naphthyridines reactions

Nitrogen nucleophiles, reactions with naphthyridines

Nucleophiles, reaction with naphthyridines

Reactions of 1,5-Naphthyridine

Reactions of 1,6-Naphthyridines

Reactions of Alkyl- and Aryl-1,5-Naphthyridines

Reactions of Amino-1,5-Naphthyridines

Reactions of Halogeno-1,5-Naphthyridines

Reactions of Nitro-1,5-Naphthyridines

Reissert reactions with naphthyridines

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