Naphthoquinones HRVs

Human rhino viruses (HRVs) are the single most significant causative agents of the common cold. HRV 3C-protease, a cysteine protease, plays a critical role in the replication cycle of HRVs and thus constitutes a potential therapeutic target for the control of HRVs and common cold. Singh et al established the structure-activity relationships of various naphthoquinones as HRV 3C-proteasa inhibitors and compared the activities of ortho- versus -para- quinones. The results indicated that the mode of action of the two classes of compounds is different [207]. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

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