Nanospheres, chitosan-based

N. Arya, S. Chakraborty, N. Dube, D.S. Katti, Electrospraying a facile technique for synthesis of chitosan-based micro/nanospheres for drug delivery appUcations, J. Biomed. Mater. Res. B 88 (1) (2009) 17-31. 

Importance of Engineering Chitosan-Based Nanoparticles, Nanospheres, and Nanogels 105... 

B., Ii, W.L, and Min, L.G. (2009) Amperometric hydrogen peroxide biosensor based on the immobilization of horseradish peroxidase on core-shell organosilica chitosan nanospheres and multiwall carbon nanombes composite. Electrochimica Acta, 54 (11), 3039-3046. 

Natural polysaccharides such as chitosan and alginate are promising materials for their applications, particularly in drug delivery, due to their favorable biocompatibility, biodegradability, pH sensitivity, and mucoadhesive properties [157, 158]. Covalently crossUnked polysaccharide-based nanospheres are quite stable compared with other several other t5q)es of polysaccharide-based nanospheres. The conventional methods for preparation of covalently crosslinked polysaccharide-based nanospheres include emulsion crosslinking, solvent evaporation, spray... 

Zhai C, Sun X, Zhao WP, Gong ZL, Wang XY (2013) Acetylcholinesterase biosensor based on chitosan/Prussian blue/multiwall carbon nanotubes/hollow gold nanospheres nanocomposite film by one-step electrodeposition. Biosens Bioelectron 42 124—130... 

Chitosan-Pmssian blue-multiwall carbon nanotube-hollow gold nanosphere (Chit-PB-MWNT-HGN) films were fabricated to be employed in AChE biosensorsIncorporating MWNTs and HGNs into a Chit-PB hybrid film promoted the electron transfer reaction, enhanced the electrochemical response, and improved the microarchitecture of the electrode surface. Based on the inhibition of the AChE activity by the pesticides malathion, chlorpyrifos, monocrotophos, and carbofuran as model compounds, the biosensor showed a wide dynamic range, low detection limit, good reproducibility, and high stability. Moreover, the AChE/Chit-PB-MWNT-HGN/Au biosensor could also be used for the direct analysis of a practical samples, which would be a new promising tool for pesticide analysis. 

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