Nanoparticles coacervation technique

Xylan-based micro- and nanoparticles have been produced by simple coacervation (Garcia et al., 2001). In the study, sodium hydroxide and chloride acid or acetic acid were used as solvent and non-solvent, respectively. Also, xylan and surfactant concentrations and the molar ratio between sodium hydroxide and chloride acid were observed as parameters for the formation of micro- and nanoparticles by the simple coacervation technique (Garcia et al., 2001). Different xylan concentrations allowed the formation of micro- and nanoparticles. More precisely, microparticles were found for higher concentrations of xylan while nanopartides were produced for lower concentrations of the polymer solution. When the molar ratio between sodium hydroxide and chloride acid was greater than 1 1, the partides settled more rapidly at pH=7.0. Regarding the surfactant variations, an optimal concentration was found however, at higher ones a supernatant layer was observed after 30 days (Garda et al., 2001). 

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