Nano solid phase extractions

Nowadays, solid phase extraction (SPE) is the technique of choice because it is inexpensive, fast, reproducible, and has a wide range of applications [43,44], 

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Qi, L. and Danielson, N.D. 2005. Quantitative determination of pharmaceuticals using nano-electrospray ionization mass spectrometry after reversed phase mini-solid phase extraction. J. Pharm. 

Up to now, most efforts have been directed towards the preparation of uniformly sized spherical MIP particles in the micrometre range. This is the obvious consequence of the need for this kind of materials as fillers for high-performance chromatographic columns, capillaries for electrophoresis, cartridges for solid-phase extractions and other applications requiring selective stationary phases. Additionally though, strategies for the preparation of other more sophisticated MIP forms, such as membranes, (nano)monoliths, films, micro- and nanostructured surfaces etc. 

In addition to electrophoresis-based collection of DNA in microchannels (see Section 7.7.3), adsorbents have been used to collect and purify DNA. In these cases, microchannels are generally used because of the small quantity of material requiring collection. Using solid phase extraction, sorbent particles of nano- and micro-silica and micro-sized octadecylsilica were immobilized using sol-gel chemistry to hU the microchannels of the microfluidic device [194]. DNA as well as several organic compoimds were evaluated for adsorption and desorption. They showed excellent adsorption, but poor recovery because they were difficult to extract. 

A sol-gel immobilization of nano an micro size sorbents in poly(dimethyl-siloxane) (PDMS) microchannels for microscale solid phase extraction (SPE). Anal. Chim. Acta 2005, 546, 22-29. 

Wang, H., Yu, S., Campiglia, A.D. Solid-phase nano-extraction and laser-excited time-resolved Shpolskii spectroscopy for the analysis of polycyclic aromatic hydrocarbons in drinking water samples. Anal. Biochem. 385, 249-256 (2009)... 

Figure X-1 Experimental distribution coefficients of Th(IV) in the TBP extraction study of [2006NEC/ALT] (aqueous phase 0.05-3 M NaNOs + 0.02 M HNO3, 22°C) and the TTA extraction study of [1950DAY/STO] (aqueous phase 0.5 M H(C104-N03), 25°C) and data evaluation using both the ion interaction model (dashed lines) and the nitrate complexation model (solid lines).

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