N-p-Trifluoromethylbenzylcinchoninium bromide

N-p-Trifluoromethylbenzylcinchoninium bromide (1). Merck chemists have reported a highly efficient enantioselectivc alkylation with a chiral phase-transfer catalyst... 

Cinchona Alkaloid-Derived Quaternary Ammonium Salts The first successful application of cinchona-based quaternary ammonium salts as chiral phase-transfer catalysts was conducted by the Merck research group in 1984 [16]. Dolling and coworkers reported the N-p-trifluoromethylbenzylcinchoninium bromide 11a for the highly enantioselective alkylation of indanone derivatives imder phase-transfer conditions (Figure 12.3). 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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