N-Methylphenethylamine

N-methyltyramine, the immediate biosynthetic precursor of hordenine, was synthesized and nitrosated in aqueous acid. The major product was U-hydroxy-3-nitro-N-nitroso-N-methylphenethylamine. 

Apparently, minor chemical modifications of the benzilcarboxylic acid containing molecules led to a compound which shows surprising analgesic activity. Condensation of N-methylphenethylamine 74 with... 

METHYL PENTYL KETONE see MGN500 METHYL-N-PENTYLNITROSAMINE see AOLOOO METHYLPERONE HYDROCHLORIDE see FKIOOO ( )-a-METHYLPHENETHYLAMINE see BBKOOO dl-Ot-iMETHYLPHENETHYLAAENE see BBKOOO a-METHYLPHENETHYK-lMINE, d-FORM see AOA500 d-a-METHYLPHENETHYLAMINE SULFATE see BBK500... 

Amino-l-(3-hydroxyphenyl)ethanol has been prepared by an improved and possibly general method for this class of compounds.16 An interesting report on the partial asymmetric induction in the reduction of acetophenone-N-benzylimine at the mercury cathode with chiral supporting electrolytes may have potential for the chiral synthesis of alkaloids.17 For example, using ( -)-(R, S)-JV-methyI-ephedrine methiodide as the electrolyte resulted in the formation of (—)-(R)-N-benzyl-a-phenethylamine of 7.3% optical purity. Of interest for biosynthetic studies are the reports of the preparation of specifically labelled substituted -phenethylamines18 and of (+)-N-(o-chlorobenzyl)-a-methylphenethylamine hydrochloride 14C-labelled at the -carbon.19... 

Benzeneethanamine, 4-(iodo- l)-a-methyl-N-(1-methyl-ethyl)-, hydrochloride, ( )- ( )-p-lodo- l-N-isopropyl-a-methylphenethylamine hydrochloride lofetamine hydro-chloride l lofetamine l hydrxhioride ( l)( )-N-lsopropyl-p-iodoamphetamine hydrochloride Perfus-amine Spectamine. Lipid-soluble radioactive brain imaging agent. Crystals mp= 156-158°. 

Of a series of 35 a- and of S-alkyl substituted phenethylamines being investigated for CNS effects, two compounds, B-1268 (Via) and B-1279 (VIb) were reported to be comparable to chlorphentermine in reducing food and bouillon consumption in rats. 3 dl-p-Chloro-N-(cyclopropy]. methyl)-or-methylphenethylamine A-3196O (VIl) has been compared to methamphetamine and diethylpropion (VIll) in man. It was found to have comparable activity in respect to appetite suppression and CNS stimulation to methamphetamine and diethylpropion. 

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