N analog

NaHC03 and recrystallize from acetonitrile. Dissolve 4.3 g (T) in 30 ml anisole and add 0.1 M methyl Mgl in 50 ml anisole. Stir 12 hours and evaporate in vacuum or acidify with sulfuric acid, neutralize with NaHC03 and filter wash to get 2.4 g N-benzyl analog of THC. For other N-analogs of unknown activity see JOC 3(5,2995(1968). Recover unreacted olivetol as usual. 

Similarly, Munoz-Guerra et al. [72] synthesized (2S, 3S )-2,3-di-methoxy-l,4-butanediamine (41) from natural L-tartaric acid as raw material to prepare stereoregular polytartaramides 87 (Nylon 4,n analogs). 

Methylation of dipolar ions 68 occurs exclusively at sulfur to yield, e.g., Ij 6i.62. N-analogs 71 give a mixture of products from methylation at both the exo- and the endocyclic nitrogen atoms. ... 

Pyrido[ 1,2-a]py rimidines represent a simple bicyclic ring system that contains a nitrogen-bridgehead condensed pyrimidine moiety. Synthetic methods for these compounds can often be applied to the preparation of similar bi- and polycyclic ring systems (e.g., benzologs, N-analogs, five membered congeners, and so on) and their reactivities are sometimes similar to those of the above-mentioned derivatives. 

Authentic N-analogs of spirobenzopyrans, the 1,2-dihydrospiro-2//-quinolines (79) (or their open forms), have never been isolated, despite many attempts during the past 35 years. In reactions with Fischer s base, 5-nitro-2-aminosalicylaldehyde gave no reaction, whereas 2-aminobenzaldehyde gave only a polymer.7 The open form of the desired compound could be considered a quinone monoimine and therefore be expected to have poor stability. 

Scheme 3. Azlactones (6) and oxazinones (7) - cyclic and N-analogous amino acid anhydrides...

Within this section, it is appropriate to point out that there is interest in preparing isoelectronic B-N analogs of the newest form of carbon, and this offers a... 

Cr N(CH2CH2PR2) X]+ (R = Cy, Ph), and the N analogs [Cr N(CH2CH2NR2) X]+ (R = Me, Et). These complexes are thonght to adopt trigonal bipyramidal structures in which the coordinated hahde occupies an axial position. 

I n analogy to other- better u nderstood - receptor systems like some hormone and opiate receptors it is generally accepted that the olfacto receptors are proteins, and there are some facts known that support this hypothesis. One of these arguments is that, sometimes, slight modification of the chemical structure of a stimulus molecule can lead to big changes in the odor impression this might be qualitative or quantitative. 

Upon photolysis of a diazo compound, the C N bond cleaves in heterolytic fashion, N2 is lost, and a carbene is generated, usually in the triplet form. Triplet carbenes have one electron in each of two orbitals and may be thought of as 1,1-diradicals. Alkyl and acyl azides also undergo loss of N2 upon photolysis. The products are highly reactive nitrenes, the N analogs of carbenes. 

The B/N analog of polyacene (40) has like the parent species, not been made but our arguments would predict that it too will have the B and N atoms in an alternating arrangement as shown. The structure of a heteropolyacene type structure of stoichiometry AlSn is however known 41, in Ba3Al2Sn2. Here the structure contains... 

Conformational space and dynamic stereochemistry of dixantylene and its S- and N-analogs 01EJO15. 

---