Myosin heavy chain splicing

A major difference between prokaryotes and eukaryotes is the presence of intervening sequences (introns) between the coding sequences (exons) in eukaryotes. Introns are especially numerous in higher organisms. For example, the gene for the myosin heavy chain present in rat embryonic skeletal muscle encodes a 1939-residue peptide but occupies a length of 22 kb of DNA. The gene is split into 41 exons, whose transcribed RNA must be cut and spliced at 40 places to form the mRNA. By compari-... [Pg.627]

Ashton FT, Somlyo AV, Somlyo AP (1975) The contractile apparatus ofvascular smooth muscle intermediate high volt e stereo electron microscopy. J Mol Biol 98 17-29 Babij P (1993) Tissue-specific and developmentally regulated alternative splicing of a visceral isoform of smooth muscle myosin heavy chain. Nucleic Adds Res 21 1467-1471... [Pg.47]

Babij P (1993) Tissue-specific and developmentally regulated alternative splicing of a visceral isoform of smooth muscle myosin heavy chain. Nucleic Adds Res 21 1467-1471... [Pg.117]

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