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Myeloperoxidase-H2O2- chloride

H2O2 reacts, for example, with chloride to form HOCl (hypochloiic acid), which is known as bleach and renowned for antibacterial activity. Formation of HOCl in vivo is catalyzed by myeloperoxidase. Its importance is underscored by the fact that people lacking that enzyme suffer from a quite pronounced immune deficiency, in particular with respect to bacterial infections. [Pg.109]

Secondly, in neutrophils and monocytes the oxidizing potential of H2O2 is greatly enhanced by the primary granule enzyme myeloperoxidase (MPO), which utilizes H2O2 to oxidize chloride ions to hypochlorous acid (HOCl). [Pg.270]

See other pages where Myeloperoxidase-H2O2- chloride is mentioned: [Pg.854]    [Pg.855]    [Pg.248]    [Pg.249]    [Pg.252]    [Pg.360]    [Pg.204]    [Pg.824]    [Pg.824]    [Pg.2]    [Pg.6]    [Pg.63]    [Pg.43]   
See also in sourсe #XX -- [ Pg.94 ]



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Myeloperoxidase

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