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Mycolic acids biological activity

The deacetylation of this product with sodium methoxide or hydroxyl-amine (mycolic acid esters react very slowly with hydroxylamine) gives, in rather low yield, a 6,6 -di-0-(3-hydroxy-x-methoxymycolanoyl)trehalose, m.p. 40-42°, [a]D -f 132°, CissHsvoOi 10 CH2 (9b), with an infrared spectrum identical with that of the natural cord-factor the biological activity of this compound was indistinguishable from that of natural cord-factor. ... [Pg.215]

With a view to studying the influence of the C-3-hydroxyl group of the mycolic acids on the biological activity of trehalose esters, trehalose was also esterified with the unsaturated acid (18) obtained by dehydration of the C44-mycolic acid (14). [Pg.217]

It was believed for a long time that biological activity was due essentially to the mycolic acids as typical constituents of mycobacteria. [Pg.3]

See other pages where Mycolic acids biological activity is mentioned: [Pg.558]    [Pg.170]    [Pg.151]    [Pg.204]    [Pg.235]    [Pg.79]    [Pg.166]   
See also in sourсe #XX -- [ Pg.230 , Pg.235 ]



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Biological acids

Mycolic acids

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