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Muscle relaxants baclofen

The y-lactone problem is made easier because the FGs are all based on oxygen. The molecule can therefore be disconnected without FGl except for oxidation or reduction. Let s now look at the synthesis of a molecule with a difficult FG the muscle relaxant baclofen TM 349. What is the difficult FG ... [Pg.113]

A second GABA receptor subtype, the GABA-B receptor (Fig. 8—12) is not allo-sterically modulated by benzodiazepines but binds selectively to the muscle relaxant baclofen. Its physiological role is not well known yet, but does not appear to be closely linked to anxiety disorders or to anxiolytics. [Pg.313]

NITRATES 1. ANALGESICS-nefopam 2. ANTIARRHYTHMICS -disopyramide, propafenone 3. ANTIDEPRESSANTS-TCAs 4. ANTI EMETICS-cydizine 5. ANTIHISTAMINES -chlorphenamine, cyproheptadine, hydroxyzine 6. ANTIMUSCARINICS -atropine, benzatropine, cydopentolate, dicydover-ine, flavoxate, homat-ropine, hyoscine, orphenadrine, oxybutynin, procyclidine, propantheline, tolterodine, trihexyphenidyl, tropicamide. 7. ANTI-PARKINSON S DRUGS-dopaminergics 8. ANTI-PSYCHOTICS - pheno-thiazines, clozapine, pimozide 9. MUSCLE RELAXANTS-baclofen 1. t risk of antimuscarinic side-effects when isosorbide dinitrate is co-administered with these drugs 2. 1 efficacy of sublingual nitrate tablets... [Pg.131]

MAOIs MUSCLE RELAXANTS-BACLOFEN, TIZANIDINE t hypotensive effect Additive hypotensive effect Monitor BP at least weekly until stable. Warn patients to report symptoms of hypotension (light-headedness, dizziness on standing, etc.)... [Pg.167]

LEVODOPA MUSCLE RELAXANTS-BACLOFEN Reports of CNS agitation and i efficacy of levodopa Uncertain Avoid co-administration... [Pg.249]

INSULIN MUSCLE RELAXANTS -BACLOFEN 1 hypoglycaemic effect of insulin Due to these drugs causing hyperglycaemia, the mechanism being uncertain at present t doses of insulin are often required for adequate glycaemic control... [Pg.412]

ANAESTHETICS-GENERAL MUSCLE RELAXANTS -BACLOFEN, TIZANIDINE t hypotensive effect Additive hypotensive effect. Tizanidine also has a negative chronotropic effect and may cause additive bradycardia with beta-blockers and calcium channel blockers Monitor BP closely, especially during induction of anaesthesia... [Pg.496]

ALCOHOL MUSCLE RELAXANTS-BACLOFEN, METHOCARBAMOL TIZANIDINE t sedation Additive effect Warn patients advise them to drink alcohol only in moderation and not to drive if they have drunk any alcohol while taking these muscle relaxants... [Pg.719]

Toxicity The sedation produced by diazepam is significant but milder than that produced by other sedative-hypnotic drugs at doses that induce equivalent muscle relaxation. Baclofen produces less sedation than diazepam. Dantrolene causes significant muscle weakness but less sedation than either diazepam or baclofen. Tizanidine may cause drowsiness and hypotension. [Pg.248]

ANTIMUSCARINICS-atropine, benzatropine, cyclopentolate, dicyclover-ine, flavoxate, homa-tropine, hyoscine, orphenadrine, oxybutynin, procyclidine, propantheline, tolterodine, trihexyphenidyl, tropicamide 7. ANTI-PARKINSON S DRUGS-dopaminergics 8. ANTI-PSYCHOTICS - pheno-thiazines, clozapine, pimozide 9. MUSCLE RELAXANTS - baclofen... [Pg.93]

ANTIPSYCHOTICS-phenothiazines, clozapine, pimozide 9. MUSCLE RELAXANTS - baclofen 10. NITRATES - isosorbide dinitrate... [Pg.107]

CALCIUM CHANNEL BLOCKERS 9. DIURETICS 10. MUSCLE RELAXANTS-baclofen, tizanidine... [Pg.212]

MUSCLE RELAXANTS-baclofen 9. NITRATES -isosorbide dinitrate... [Pg.320]

See other pages where Muscle relaxants baclofen is mentioned: [Pg.234]    [Pg.67]    [Pg.167]    [Pg.101]    [Pg.16]    [Pg.30]    [Pg.109]    [Pg.135]    [Pg.181]    [Pg.240]    [Pg.252]    [Pg.446]    [Pg.451]    [Pg.461]    [Pg.186]    [Pg.207]    [Pg.528]    [Pg.674]   
See also in sourсe #XX -- [ Pg.204 , Pg.249 ]



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Baclofen

Baclofen, a skeletal muscle relaxant, acts at the spinal cord level to inhibit transmission of monosynaptic and polysynaptic reflexes

Muscle relaxant

Muscle relaxation

Muscle-relaxing

Skeletal muscle relaxants baclofen

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