Multiple sclerosis model

Baker D, Pryce G, Croxford JL. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 2000 404 84-87. 

Baker D, Pryce G, Croxford JL, Brown P, Pertwee RG, Makriyannis A, Khanolkar A, Layward L, Fezza F, Bisogno T, Di Marzo V. Endocanna-binoids control spasticity in a multiple sclerosis model. FASEB J 2001 15 300-302. 

The use of neural stem cells in remyelinating therapy has been explored by many researchers. Pluchino et al. (2003) successfully used adult neural stem cells to promote functional recovery in a multiple sclerosis model. Transplanted neural stem cells showed the ability to selectively reach the demy-elinating areas, where they differentiated into axon-ensheathing oligodendrocytes and achieved extensive remyehnation (Pluchino et al., 2003). 

Baker, D., Pryce, G., Croxford, J.L., Brown, P, Pertwee, R.G., Makriyannis, A., Khanolkar, A., Layward, L, Fezza, F, Bisogno, T., and Di Marzo, V. (2001) Endocannabinoids control spasticity in a multiple sclerosis model, FASEB Journal 15 300-302. 

Baker, D., G. Pryce, J.L. Croxford, P. Brown, R.G. Pertwee, J.W. Huffman, and L. Layward (2000). Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404(6773) 84—87. 

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