Mucous secretion antigens

The Nature of ABH Blood Group Antigens in Mucous Secretion... 

The release of mediators (histamine, serotonin, bradykinin etc.) from mast cells is activated by IgE-antigen interactions and their action on smooth muscle, mucus glands and blood vessels probably plays an important role in the responses to intestinal infections. For example, mucus gland secretion can be stimulated by histamine and increased mucous secretion is a characteristic of several intestinal helminth infections (80). 

Allergens attach to mast cells and basophils in connective tissues, causing an antigen-antibody reaction. Mast cells stimulate the release of chemical mediators that constrict the bronchi, increase mucous secretions, stimulate the inflammatory response, and cause pulmonary congestion. 

More than 20 blood group systems are known having 160 distinct antigenic oligosaccharide groupings. They are present on other cells as well as red blood corpuscles and are found attached to mucous secretions including saliva. 

MRT mean residence time (drug turnover time), mucosa The lining of the gut. consisting of three layers the inner epithelium lamina propria muscularis mucosae, mucous membrane (mucosa) The moist membrane lining internal structures, e.g. respiratory tract, mucus The fluid secreted by mucous membranes, multideterminant Antigen carrying more than one antigenic determinant. 

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