Mucolytics nausea

Use of codeine may result in respiratory depression, euphoria, light-headedness, sedation, nausea, vomiting, and hypersensitivity reactions. The more common adverse reactions associated with the antitussives are listed in the Summary Drug Table Antitussive, Mucolytic, and Expectorant Drugs. When used as directed, nonprescription cough medicines containing two or more ingredients have few adverse reactions. However, those that contain an antihistamine may cause drowsiness. 

Bromhexine hydrochloride (Bisolvan) is a bronchial mucolytic agent and secretagogue that may have a stimulating effect on tear secretion. Oral bromhexine and its derivative ambroxol have equivocal results in clinical trials and are associated with side effects of nausea, sweating, and rashes. 

Carbocisteine is a mucolytic that is administered oraUy or from a metered dose inhaler. Its adverse effects include headache, nausea, vomiting, gastric discomfort and bleeding, diarrhea, and skin rash. It has, however, been shown to be an effective mucolytic which is generally well tolerated with few adverse effects (SEDA-17, 208). 

Inhalation is used to deliver antibiotics, steroids and mucolytic agents (drugs that thin secretions making it easier to clear the bronchi). The patient can experience side effects such as tremors, nausea, tachycardia, palpitations, nervousness, and dysrhythmias (see Chapter 14). 

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