Probenecid Moxifloxacin

Significant drug interactions with theophylline [268], itraconazole [269], warfarin, yS-acetyldigoxin, ranitidine, probenecid and oral contraceptives have not been reported with moxifloxacin [12,237]. 

PROBENECID QUINOLONES -CIPROFLOXACIN, LEVOFLOXACIN, NALIDIXIC ACID, NORFLOXACIN t ciprofloxacin, nalidixic acid and norfloxacin levels Uncertain Watch for t incidence of side-effects. Moxifloxacin, ofloxacin and sparfloxacin do not seem to interact and could be used as alternative therapy... 

Concomitant administration of probenecid did not affect the elimination of moxifloxacin (4). 

Probenecid increases the serum ieveis and/or decreases the urinary excretion of cinoxacin, ciprofloxacin, clinafloxacin, enoxacin, fleroxacin, levofloxacin, nalidixic acid and norfloxacin. The ciinicai importance of these changes is uncertain, but is seems iikeiy they wiii oniy be important in the presence of other drugs that aiso affect renai excretion. Grepafloxacin, moxifloxacin, sparfloxacin, and probably ofloxacin, appear not to interact with probenecid. 

A study in 12 healthy subjects found that probenecid had no clinically significant effects on the pharmacokinetics of a single 400-mg dose of moxifloxacin."... 

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