Motility hyperactivated

Stauss, G.R., Votta, T.J. and Suarez, S.S. (1995). Sperm motility hyperactivation facilitates penetration of the hamster zona pellucida. Biol. Reprod. 53, 1280-1285. 

Okunade, G.W., Miller, M.L., Pyne, G.J., Sutliff, R.L., O Connor, K.T., Neumann, J.C., Andringa, A., Miller, D.A., Prasad, V., Doetschman, T., Paul, R.J., Shull, G.E., 2004, Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4. J Biol Chem 279, 33742-33750. 

Boatman, D.E and Robbins, R.S. (1991). Bicarbonate Carbon-dioxide regulation of sperm capacitation, hyperactivated motility, and acrosome reactions. Biol. Reprod. 44 806-813. 

White, D.R. and Aitken, R.J. (1989). Relationship between calcium, cyclic AMP, ATP, and intracellular pH and the capacity of hamster spermatozoa to express hyperactivated motility. Gamete Res. 22 163-177. 

FIGURE 22.4 Effects of AM356 on hyperactivated motility sperm (HA) during incubation for 6 h. (a) Incidence of HA in sperm cultured in control medium, (b) Incidence of HA in sperm treated with AM356 (0.25 nM) (closed circles) and (2.5 nM) (open circles). Data expressed as percent of control values. The effects of AMS 56 on HA at 2.5 nM were significantly different from those produced by AMS 56 at (0.25 nM) p <. 05, ANOVA). N = 6 experiments using sperm from 3 different donors. (From Schuel H et al. 2002. Mol Reprod Dev 63 376-387. With permission.)... 

Burkman LJ. 1984. Characterization of hyperactivated motility by human spermatozoa during capacitation comparison of fertile and oligospermic populations. Arch Androl 13 153-165. 

Burkman LJ. 1990. Hyperactivated motility of human spermatozoa during in vitro capacitation, in Gagnon E, Ed. Controls of Sperm Motility. Boca Raton, FL CRC Press, pp. 304-329. 

As the spermatozoa move through the uterus they continue to exhibit vigorous motility (see [83] for a review). A few of them may exhibit hyperactivated motility (see below). For traversing the uterus-oviduct junction, the spermatozoa should apparently have progressive motility [113]. In humans, only about 0.004% of the total motile cells inseminated are found in both Fallopian tubes together [49] (Figure 4). 

Burkman, L.J. (1990). Hyperactivated motility of human spermatozoa during in vitro capadtation and implications for fertility, in Gontrols of Sperm Motility Biological and Clinical Aspects (C. Gagnon, ed.), pp. 303-329. CRC Press, Boca Raton. 

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