Morus Ihou

Fukai, T., Y. Hano, K. Hirakura, T. Nomura, J. Uzawa, and K. Fukushima Constituents of the Cultivated Mulberry Tree XXV. Structures of Two Natural Hypotensive Diels-Alder Type Adducts, Mulberrofurans F and G, from the Cultivated Mulberry Tree Morus Ihou Koidz.). Chem. Pharm. Bull. (Japan) 33, 3195 (1985). 

Nomura, T., T. Fukai, Y. Hano, and H. Ikuta Kuwanon M, a New Diels-Alder Adduct from the Root Barks of the Cultivated Mulberry Tree (Morus Ihou (Ser.) Koidz.). Heterocycles 20, 585 (1983). 

Kohno, H., T. Takaba, T. Fukai, and T. Nomura Constituents of the Cultivated Mulberry Tree XXXIX. Structure of Mulberrofuran R, a Novel 2-Arylbenzofuran Derivative from the Cultivated Mulberry Tree Morus Ihou Koidz.). Heterocycles 26, 759 (1987). 

About seventy kinds of new phenolic compounds could be isolated from Japanese cultivated mulberry tree (Morus alba, M. bombycis, and M, Ihou) and Chinese crude drug Sang-Bai-Pi (the root bark of Chinese mulberry tree). Most of them are isoprenylated flavonoids. Among them, kuwanon G (1) was the first isolation of the active substance exhibiting the hypotensive effect from the Japanese Morus alba root bark [9]. Furthermore, kuwanon G (1) and its isoprenylated derivative kuwanon H (2) [10] are considered to be formed through an enzymatic Diels-Alder type reaction of a chalcone and a dehydrokuwanon C or its... 

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