Mortality, anaphylaxis

Death caused by an anaphylactic reaction to a muscle relaxant seems to be rare, although mortality rates from intraoperative anaphylaxis in the range of 3.4-6% have been reported (28-31). The incidence of cardiac arrest was 4.9% among patients with anaphylactic reactions to muscle relaxants referred to the French GERAP centers for further testing, but these patients all survived (22). 

The effect of supplementary ascorbic acid on anaphylaxis-induced mortality is shown in Table IV. A 44% reduction in mortality was noted for the ascorbic acid-treated mice compared to tap water-treated controls (p<0.01). This is the first indication that dietary ascorbic acid, without antihistamines, may provide protection against anaphylaxis-induced mortality. 

Effect of Supplementary Ascorbic Acid on Anaphylaxis-Induced Mortality in BALB/c Female Mice... 

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