Morpholine 4- 2-naphthyl

A variety of benzylamines 124 (R1 = Ph, Ar, 2-naphthyl, or 3- or 4-pyridyl etc NR22 = piperidin-l-yl or morpholin-4-yl) was obtained from benzotriazole, an aldehyde R CIIO and an amine HNR22 and subsequent reduction of the products with sodium borohydride (equation 44)125. 

Interaction of the same 1-benzy 1-3-methyl-substituted salt 184 with morpholine leads to a-naphthylamine 187 in ethanol and to the mixture of a-(187) and 8- (188) naphthyl-amines in a ratio depending on the temperature if morpholine itself was used as a solvent (88MI1 88UP1). 

Tetrahydro-l-naphthyl hydroperoxide, 3306 Tetrahydro-l,4-oxazine, see Morpholine, 1652... 

N1 - MORPHOLINE 4-12-1 p-l 6-ME7HOXY-2-PHENYL-3,4-OIMYDRO l-NAPHTHYL)PHENOXY )ETHYD- - HYDROCHLORIDE... 

A mixture of 373 g (2.2 mol) of methyl 2-naphthyl ketone, 105 g (3.3 mol) of sulfur, and 290 g (3.3 mol) of morpholine is refluxed gently for 14 h and briskly for 2 h in a hood. While still hot, the mixture is poured into 1.2 L of warm ethanol. After the mixture has been cooled, 534 g (89.6%) of pale-buff crystals of 2-naph-thylacetic add thiomorpholide, mp 100-106 °C, is obtained. A mixture of 388 g (1.61 mol) of the thiomorpholide, 800 mL of acetic add, 120 mL of concentrated sulfuric acid, and 180 mL of water is refluxed for 5 h and then poured into 6 L of water. A considerable amount of tar is left in the flask. After the mixture has been allowed to stand overnight, the solid is collected, washed with water, and digested... 

Starch reacts with isocyanates to produce carbamates (urethanes), which are esters of carbamic acid. Several reactions of starch with phenyl-, various aryl-, 1-naphthyl-isocyanates or 1,6-hexamethylene- and 2,4-tolyl-diisocyanates were conducted either in pyridine or morpholine below the boiling point of these solvents.2546-2548 In each case all three hydroxyl groups of the glucose units reacted to give tricarbanilates, provided a sufficient amount of the isocyanate reagent was used. 

NR2 NHalkyl, cycloalkylamine, NHaryl, pyrrolidine, substituted piperidine, substituted morpholine Ar = Ph, 3-Tol, 4-CIC6H4, 4-02NC,6H4, 2-thienyl, 2-pyridyl, 2-naphthyl... 

NEM. See Ethyl morpholine Nemacut . See Fenamiphos Neo 913 Acid. See C9-13 neo fatty acids Neo-DNPD. See N,N -Di-P-naphthyl-p-phenylenediamine... 

Glyoxylic acid monohydrate in ethanol stirred 30 min. at room temp, with morpholine, / -naphthol added, refluxed 1 hr., the solvent distilled off in vacuo, and the residue dissolved in 3 N HGl -> morpholino-(2-hydroxy-l-naphthyl)-acetic acid hydrochloride. Y 85-90%. F. e. s. E. Biekert and T. Funck, B. 97, 363 (1964). 

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