Montana Department of Agriculture

In 1985, 1080 use was conditionally permitted in livestock protection collars and in single lethal dose baits a registration for the livestock protection collar was issued to the U.S. Department of the Interior on July 18, 1985 (USEPA 1985). On Lebruary 21, 1989, the registration for 1080 was canceled, effectively prohibiting all uses. In June 1989, however, technical 1080 was conditionally approved for use only in the 1080 livestock protection collar. The 30-mL collar is registered for use by the U.S. Department of Agriculture by the states of Montana, Wyoming, South Dakota, and New Mexico and by Rancher s Supply, Alpine, Texas (Palmateer 1989, 1990). 

This fungus was identified as a Penicillium sp. by Dr. Gene Ford of the Department of Plant Pathology, Montana State University, and was deposited in the Agricultural Research Culture Collection (NRJ 21208). Penicillium sp. isolate HIRE produced a number of compounds which were isolated by either bioassay-guided or NMR activity -guided fractionation. Two novel bioactive metabolites are currently being characterized, but the isolation and identification of several other compounds will be described below. 

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