Monooxygenases oxidation

The November 2001 issue of the Journal of Chemical Education ipp 1533-1534) describes an introductory biochemistry laboratory ex periment involving cycio hexanone monooxygenase oxidation of cyclic ketones... 

This suggestion is already known. Indeed in 1969, it was stated [130] that monooxygenase oxidation of some aromatic compounds produced intermediates, shaped as epoxides of these aromatics ... 

Schneider, S., Wubbolts, M. G., Sanglard, D., and Witholt, B. 1999. Production of alkanedioic acids by cytochrome P450(BM-3) monooxygenase Oxidation of 16-hydroxyhexadecanoic acid to hexadecane-l,16-dioic acid. Biocatalys. Biotransform., 17,163-178. 

Monooxygenases, oxidizing enzymes Oxidation, Baeyer—ViUiger oxidation... 

B) The action of squalene monooxygenase oxidizes carbon 14 of the squalene chain, forming an epoxide. 

Biosynthesis of norepinephrine takes piace within adrenergic neurons near the terminus of the axon and junction with the effector cell. The biosynthetic pathway (Fig. 13,1) begins with the active transport of the amino acid L-tyrosine into the adrenergic neuron cell (1). In the first step within the cytoplasm, the enzyme tyrosine hydroxylase (tyrosine-3-monooxygenase) oxidizes the 3 position of tyrosine to form the catechol amino acid L-dopa. This is the rate-limiting step in norepinephrine biosynthesis, and the activity of tyrosine hydroxylase is carefully controlled (3). The enzyme is under feedback inhibition control by product catecholamines and is... 

Syed K, Doddapaneni H, Subramanian V, Lam YW, Yadav JS (2010) Genome-to-funetion eharacteriza-tion of novel fungal P450 monooxygenases oxidizing polyeyelie aromatie hydroearbons (PAHs). Bio-ehem Biophys Res Commun 399 492 97... 

Shen B, Hutchinson CR. Teiracenomycin FI monooxygenase Oxidation of a nafditha cenone to a naphthacenequinonc in the biosynthesis of tetracenomycin C in Streptomyces... 

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