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Mononuclear phagocytes Macrophages Monocytes

Also termed the mononuclear phagocytic system, monocytes circulate in the blood and macrophages in the tissues. In the bone marrow during hematopoiesis, the... [Pg.13]

Two major classes of WBCs are involved in removing invading microorganisms by a process of phagocytosis. These are polymorphonuclear leukocytes and mononuclear phagocytes, or monocytes. In tissues, monocytes differentiate into macrophages and, in the brain, into microglia... [Pg.433]

The very early peak of neutrophil invasion into an inflamed area is followed several hours later by a wave of a second class of phagocytic cells, the macrophages. This biphasic pattern of inflammatory cell movement and accumulation is observed in most acute inflammatory responses. The mononuclear phagocyte in the blood is known as the monocyte and differentiates... [Pg.628]

CSF-1 (also known as macrophage CSF or M-CSF) locally and humorally regulates the survival, proliferation, differentiation and function of mononuclear phagocytic cells (committed progenitor, monoblast, promonocyte, monocyte, tissue... [Pg.67]

Monocytic. Pertaining to or, characterized by a mononuclear phagocytic leukocytes, formed in bone marrow and transported to tissues, as of the lung and liver, where they develop into macrophages. [Pg.572]

The Mononuclear Phagocyte System as a Source of Wound-Site Monocytes and Macrophages... [Pg.29]

Nibbering PH, Leijh PC, van Furth R (1987) Quantitative immunocy-tochemical characterization of mononuclear phagocytes I. Mono-blasts, promonocytes, monocytes, and peritoneal and alveolar macrophages. Cell Immunol 105 374—385. [Pg.105]

A monocyte is a mononuclear phagocyte in the blood. Monocytes have free access via fenestrated capillaries to most organs in the body where they can become tissue-specific macrophages. The CNS represents an exceptional organ in that its capillaries are nonfenestrated and the endothelial cells form tight junctions which, in essence, constitute the blood-brain barrier. Thus, all blood leukocytes, including monocytes, are normally prohibited from entering the CNS. [Pg.80]

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Monocytes

Monocytes monocytic

Phagocytes

Phagocytic

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