Monochlorodifluoromethane

Chloroform was used chiefly as an anesthetic and in pharmaceutical preparations immediately prior to World War II. However, these uses have been banned. Annual output in both the United States and the United Kingdom was between 900 and 1350 metric tons. During the war, chloroform production in the United States tripled, largely to meet the requirement for penicillin manufacture. Demand for chloroform continued to increase in the postwar period as its technical appHcations were extended. Consumption continues to increase at a comparatively rapid rate. Chloroform is now used primarily in the manufacture of HCFC-22, monochlorodifluoromethane, a refrigerant, and as a raw material for polytetrafluoroethylene plastics. 

At 225—275°C, bromination of the vapor yields bromochloromethanes CCl Br, CCl2Br2, and CClBr. Chloroform reacts with aluminum bromide to form bromoform, CHBr. Chloroform cannot be direcdy fluorinated with elementary flourine fluoroform, CHF, is produced from chloroform by reaction with hydrogen fluoride in the presence of a metallic fluoride catalyst (8). It is also a coproduct of monochlorodifluoromethane from the HF—CHCl reaction over antimony chlorofluoride. Iodine gives a characteristic purple solution in chloroform but does not react even at the boiling point. Iodoform, CHI, may be produced from chloroform by reaction with ethyl iodide in the presence of aluminum chloride however, this is not the route normally used for its preparation. 

Treatment of chloroform, obtained by reacting methanol and chlorine, with the hydrofluoric acid yields monochlorodifluoromethane, also used as a refrigerant, which is a gas boiling at -40.8 C. 

The monochlorodifluoromethane may be converted to tetrafluoroethylene by pyrolysis, for example by passing through a platinum tube at 700°C. 

Langenfeld et al. [48] also compared supercritical monochlorofluoromethane, nitrogen dioxide and carbon dioxide for the extraction of polyaromatic hydrocarbons from sediments. Monochlorodifluoromethane provided the highest recoveries. 

T richlorofluorome thane Dichlorodifluoromethane Monochlorodifluoromethane Isovaleraldehyde Isovaleraldehyde Isovaleraldehyde Diisobutyl Ketone Benzene Hexachloride Oil, Range... 

Monochlorethanoic Acid, Ethyl Ester Monochloroacetic Acid Monochlorobenzene Monochlorodifluoromethane Monochloromethyl Ether... 

TFE is obtained by the thermal decomposition of this monochlorodifluoromethane (known as Freon) in a continuous noncatalytic gas-phase reaction, carried out at or below atmospheric pressure at temperatures from 600 to 900°C ... 

MONOCHLOROBENZENE see CEJ125 MONOCHLORODIFLUOROMETHANE see CFX500 MONOCHLORODIMETHYL ETHER (MAK) see CIO250... 

Synonyms/Trade Names Difluorochloromethane, Fluorocarbon-22, Freon 22, Genetron 22, Monochlorodifluoromethane, Refrigerant 22 ... 

FC 22 Fluorocarbon 22 Freon 22 HCFC 22 Hydrochlorofluorocarbon 22 (INCI) Monochlorodifluoromethane Propellant 22 R 22 Refrigerant 22... 

Monochlorobenzene. See Chlorobenzene Monochlorodibromomethane. See Chlorodibromomethane Monochlorodifluoromethane. See Chlorodifluoromethane Monochlorodimethyl ether. See Chloromethyl methyl ether... 

MIBC Methyl Amyl Alcohol Monochlorodifluoromethane Monochlorodifluoro-... 

Compound Name Bisphenol A T richlorofluoromethane Dichlorodifuoromethane Monochlorodifluoromethane 1,1 -Dimethylhydrazine... 

Chtofottuoromelhanes 60 100-180 38-82 E E dichloromonoNuoromethane and monochlorodifluoromethane. hydrogen chloride 20% hydrogen fluoride 10% chloroform 5%. antimony pentachloride. oxygen, nitrogen, total 5% (approx.) water not over 200 ppm. 

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