Monascus rubber

Lovastatin and mevastatin Lovastatin, (lS,3R,7S,8S,8aR)-l,2,3,7,8,8a-hexahydro-3, 7-dimethyl-8-[-[2R,4R]-[tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-l-naphthyl (S)-2-methylbutyrate (20.2.7) is isolated from Monascus rubber [17] mA Aspergillus terreus [18], as is mevastatin (lS,3R,7S,8S,8aR)-l,2,3,7,8, 8a-hexahydro-7-metliyl-8-[-(2R,4R)-[tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-l-naphthyl (S)-2-metliylbutyrate (20.2.8), which is isolated from Penicillium citrinum [19, 20] as well as from Penicillium brevicom-pactum [21]. 

Endo, A., Hasumi, K., and Negishi, S. 1985b. Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus rubber. J. Antibiot. (Tokyo) 38(3), 420 22. 

Hajjaj, H., Blanc, P. J., Groussac, E., Goma, G., Uribelarrea, J. L., and Loubiere, P. 1999a. Improvement of red pigment/citrinin production ratio as a fimction of environmental conditions by Monascus rubber. Biotechnol. Bioeng. 64(4), 497-501. 

Hajjaj, H., Klaebe, A., Loret, M. O., Goma, G., Blanc, P. J., and Francois, J. 1999b. Biosynthetic pathway of citrinin in the filamentous fungus Monascus rubber as revealed by 13C nuclear magnetic resonance. Appl. Environ. Microbiol. 65(1), 311-314. 

Vandenplas, O., Caroyer, J. M., Cangh, F. B., Delwiche, J. P., Symoens, F., and Nolard, N. 2000. Occupational asthma caused by a natural food colorant derived from Monascus rubber. J. Allergy Clin. Immunol. 105(6 Pt. 1), 1241-1242. 

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