Tissue engineering scaffolds molecular self-assembly

Besides traditional 3-D scaffolds fabrication methods, electrospinning and molecular self-assembly are newly developed techniques to construct biomimetic polymer scaffolds. Scaffolds fabricated by those techniques are mainly used in four tissue engineering areas skin, cartilage, blood vessel, and nerve. 

Abstract Molecular self-assembly is a powerful approach being explored for novel supra-molecular nanostructures and bio-inspired nanomaterials. In this article, we focus on recent research concerning the self-assembly of de novo designed artificial peptides and peptidomimetics into nanofiber structures, specifically towards developing a new class of soft-materials. These nanofiber architectures have potential use not only in biomedical applications, such as 3D-matrix scaffolds for tissue engineering and biomineralization, but also in nanotechnology such as nano-templates and dimension-regulated functional nano-objects. 

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