Molecular recognition technology

S.S. Iqbal, M.W. Mayo, J.G. Bruno, B.V. Bronk, C.A. Batt and J.P. Chambers, A review of molecular recognition technologies for detection of biological threat agents, Biosens. Bioelectron., 15 (2000) 549-578. 

Izatt, N.E., Bruening, R.L., Krakowiak, K.E. and Izatt, S.R. (2000) Contributions of Professor Reed M. Izatt to molecular recognition technology from laboratory to commercial application, Ind. Eng. Chem. Res. 39, 3405-3411. 

Izatt, R. M., Bradshaw, J. S., Bruening, R. L., and Bruening, M. L. (1994) Solid Phase Extraction of Ions of Analytical Interest using Molecular Recognition Technology, Amer. Lab 26, 28C-28M. 

A recent approach to producing highly selective sorbents for SPE is based on molecular recognition technology and utilizes antibodies immobilized by covalent reaction onto solid supports such as silica (Figure 2.30). Preparation of immunoaffinity sorbents for SPE was reviewed by Stevenson [101] and Stevenson et al. [102], Using immunosorbents, efficient cleanup is achieved from complex biological and environmental samples. 

In Table 2, some desirable features of an effective separation system are given. It is apparent that these requirements pose severe challenges for any separation procedure. Traditional technologies fail on many of the points given in Table 2. However, the molecular recognition technology (MRT) approach has enabled IBC to develop new separation systems tailored to specific needs in several industries. Examples of these systems will be presented and discussed. 

COMMERCIAL SEPARATIONS USING MOLECULAR RECOGNITION TECHNOLOGY... 

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